Epigenetic markers as predictors of neurodegeneration in long COVID survivors

Authors

  • Ali Aghajan Department of Physics, University of Hamburg, D-20355, Hamburg, Germany
  • Seyed Ali Hosseini Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran
  • Shahab Mahmoudvand Department of Virology, School of Medicine, Hamadan University of Medical Science, Hamadan, Iran http://orcid.org/0000-0002-9155-9939

DOI:

https://doi.org/10.61882/jcbior.6.2.315

Keywords:

Long COVID, SARS CoV 2, Epigenetic, Neurodegeneration, Biological aging

Abstract

No abstract.

References

1. Farkas G, Mahdaouy ZE, Babszky G, Jokai M, Torma F, Gu Y, et al. Associations of epigenetic aging and COVID-19: A 3-year longitudinal study. Geroscience. 2025;47(3):4889-4898.

DOI: 10.1007/s11357-025-01635-4 PMID: 40210827

2. Calzari L, Dragani DF, Zanotti L, Inglese E, Danesi R, Cavagnola R, et al. Correction: Epigenetic patterns, accelerated biological aging, and enhanced epigenetic drift detected 6 months following COVID 19 infection: insights from a genome wide DNA methylation study. Clin Epigenetics. 2024;16(1):158.

DOI: 10.1186/s13148-024-01764-1 PMID: 39543717

3. Shekhar Patil M, Richter E, Fanning L, Hendrix J, Wyns A, Barrero Santiago L, et al. Epigenetic changes in patients with post-acute COVID-19 symptoms (PACS) and long-COVID: A systematic review. Expert Rev Mol Med. 2024;26:e29.

DOI: 10.1017/erm.2024.32 PMID: 39435694

4. Hong P, Waldenberger M, Pritsch M, Gilberg L, Brand I, Bruger J, et al. Differential DNA methylation 7 months after SARS-CoV-2 infection. Clin Epigenetics. 2025;17(1):60.

DOI: 10.1186/s13148-025-01866-4 PMID: 40251596

5. Rasmi Y, Shokati A, Hassan A, Aziz SG, Bastani S, Jalali L, et al. The role of DNA methylation in progression of neurological disorders and neurodegenerative diseases as well as the prospect of using DNA methylation inhibitors as therapeutic agents for such disorders. IBRO Neurosci Rep. 2022;14:28-37.

DOI: 10.1016/j.ibneur.2022.12.002 PMID: 36590248

6. Humaira Amanullah F, Alam T, El Hajj N, Bejaoui Y. The impact of COVID-19 on "biological aging". Front Immunol. 2024;15:1399676. DOI: 10.3389/fimmu.2024.1399676

PMID: 38919619

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Published

2025-06-30

Issue

Section

Letter

How to Cite

Epigenetic markers as predictors of neurodegeneration in long COVID survivors. (2025). Journal of Current Biomedical Reports, 6(2), 49-50. https://doi.org/10.61882/jcbior.6.2.315

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